Engineering Thesis Defenses

We are pleased to announce the successful defense of several engineering theses by our graduates, whose innovative research has significantly advanced the field of nanomaterials. Their projects, centered on the synthesis, characterization, and application of gold nanoparticles, contribute to cutting-edge developments in biomedical diagnostics, targeted therapies, and advanced materials.

Eng. Malwina Hamera
Thesis Title: “Synthesis and Application of Anisotropic, Morphologically Chiral Gold Nanoparticles in pELISA Targeting TNFα Detection”
Summary: This study demonstrates a correlation between the chiroptical response of anisotropic, morphologically chiral gold nanoparticles and TNFα concentration. The findings pave the way for innovative strategies in ultrasensitive biomedical diagnostics.
Supervisor: dr hab. Michał Wójcik

Eng. Tomasz Kluczek
Thesis Title: “Large-Scale Synthesis of Gold Nanobipyramids for Biological Applications”
Summary: This research optimizes the Growth-to-Seed (GtS) method for synthesizing gold nanobipyramids, achieving precise control over their size and optical properties. The improved scalability resulted in a 100-fold increase in nanoparticle yield compared to traditional methods, with each reaction producing 50 mg of uniform nanobipyramids.
Supervisor: dr hab. Wiktor Lewandowski

Eng. Weronika Kondej
Thesis Title: “Release of Anticancer Drugs from Gold Nanoparticles in a Proteolytic Environment and Reduced pH: A Case Study of Doxorubicin and Crizotinib”
Summary: Focusing on the use of gold nanoparticles as drug carriers for anticancer therapy, this thesis evaluates conjugates with doxorubicin and crizotinib. The controlled release of active substances under low pH and proteolytic conditions indicates potential improvements in targeted cancer therapies.
Supervisor: dr hab. Michał Wójcik

Eng. Amelia Kostecka
Thesis Title: “Synthesis and Use of Anisotropic Gold Nanoparticle Conjugates for Construction of Ultrasensitive Lateral Flow Immunoassays”
Summary: The research aimed to lower the detection limit of lateral flow tests by utilizing anisotropic gold nanoparticle conjugates, specifically gold nanotriangles, resulting in enhanced sensitivity compared to conventional approaches.
Supervisor: dr Maciej Bagiński

Eng. Artur Le Hoang
Thesis Title: “Multidentate Hybrid Compounds as Chirality Inducers in the Synthesis of Morphologically Chiral Anisotropic Gold Nanoparticles”
Summary: This research investigates the potential of multidentate hybrid compounds to induce chirality in the synthesis of anisotropic gold nanoparticles. By establishing correlations between the morphological and chiroptical properties of the synthesized nanoparticles and the characteristics of the inducers, the study provides valuable insights for the controlled design of chiral plasmonic nanomaterials.
Supervisor: dr hab. Wiktor Lewandowski

Eng. Zuzanna Woźniak
Thesis Title: “Application of Gold Nanoparticles with Diverse Metallic Core Morphologies in the Development of Lateral Flow Assays with Lowered Detection Limits”
Summary: This study focuses on optimizing lateral flow assays through the synthesis of gold nanoparticle conjugates with various morphologies. Utilizing C-reactive protein antibodies as reporters, the research demonstrates the potential for significantly enhanced antigen detection sensitivity.
Supervisor: dr Maciej Bagiński

Eng. Mateusz Zarzeczny
Thesis Title: “Multilevel Control of Chiroptical Properties in Morphologically Chiral Liquid Crystalline Phases”
Summary: This thesis explores three distinct approaches to controlling the physicochemical properties of morphologically chiral liquid crystalline phases in thin films. The research highlights the influence of molecular architecture, gold nanoparticle doping, and photothermal remelting on the morphology, size, and chiroptical activity of these structures, suggesting promising applications in advanced materials and anti-counterfeiting technologies.
Supervisor: dr hab. Wiktor Lewandowski

We extend our sincere congratulations to all the graduates and wish them continued success in their future endeavors.